From features to expression: High-density oligonucleotide array analysis revisited.
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From features to expression: High-density oligonucleotide array analysis revisited
One of the most popular tools for large scale gene expression studies are highdensity oligonucleotide (GeneChip R ) arrays. These currently have 16-20 small probes (“features”) for evaluating the transcript abundance of each gene. In addition, each probe is accompanied by a mismatched probe (MM) designed as a control for non-specificity. An algorithm is presented to compute comparative expressi...
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